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Research
The following is a compilation of some of the most important research in support of the Bale/Doneen method and the oral systemic practice assumptions.
1
Bale/Doneen causal relationship article
2
Periodontal pathogen AA and its effects on endothelial cells
3
Changes in clinical and microbiological periodontal profiles relate to progression of carotid intima-media thickness
4
Associations between chronic periodontitis/edentulism and risk of coronary heart disease
5
Concordia study showing lower healthcare cost across the board for patients under periodontal maintenance
6
Periodontal disease and Lp-Pla2 inflammatory biomarkers
7
Periodontal disease and stroke risk
8
Periodontal disease associated with heart attack risk
9
Oral infections and vascular disease study (INVEST)
10
Periodontal disease and coronary plaque
11
Oral pathogens in acute coronary syndrome thrombi
12
Periodontal pathogens in carotid atheroma
13
Periodontal pathogen (Pg) invasion of heart cells and endothelial cells
14
Microbiological parameters in patients with acute myocardial infarction
15
Periodontal disease and inflammation
16
Periodontology and Caridiology consensus report
17
Periodontitis increases risk of first myocardial infarction
18
Periodontal therapy and regression of carotid IMT score
19
Coronary heart disease and tooth loss
20
Oxidative stress and oral bacteria
21
Periodontal disease and pancreatic cancer
22
Periodontal disease and obstructive sleep apnea
23
Periodontal disease and breast cancer
24
Periodontal pathogen (Pg) and esophageal cancer
25
Oral pathogens disrupt immune response
26
Periodontal disease and lung cancer
27
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39
Periodontal disease and chronic kidney disease
Periodontal pathogen (Pg) and arthritis
Periodontal pathogens, osteoarthritis and periprosthetic infections of knee
Periodontal disease and diabetes
Periodontal disease and low birth weight risk
Periodontal disease and cognitive decline in Alzheimer's patients
Periodontal disease, cognitive impairment, and dementia
Periodontal disease treatment lowers cancer risk
Periodontal disease and venous thromboembolic disease
Periodontal pathogens in coronary atherosclerotic plaque
Periodontal pathogen (Pg) interactions with human coronary artery endothelial cells
Oral bacteria found in 90% of unhealthy heart valves
Periodontal disease and pre-hypertension/hypertension
40
Periodontal pathogens linked to low HDL and high triglycerides
41
Periodontal pathogens in carotid atheroma
42
Cardiovascular and cerebrovascular disease secondary to oral infection
43
Glomerulonephritis secondary to oral infection
44
Bacterial endocarditis secondary to oral infection
45
Periodontal pathogen (Pg) is the most abundant species detected in coronary and femoral arteries.
46
Periodontal pathogen (Pg) is involved in the pathogenesis of diabetes mellitus (DM).
47
Periodontal pathogen increases colorectal cancer mortality
48
High Lp-PLA2 doubles risk for Alzheimers
49
Periodontal pathogens and oxidative stress
50
Periodontal pathogens and rheumatoid arthritis
51
The use of phase contrast microscopy is useful in periodontal risk assessment
52
The use bleach as an oral antimicrobial
53
History of periodontitis, diagnosis and edentulism as predictors of cardiovascular disease, stroke, and mortality in postmenopausal women
54
Links between oral health and general health: The case for action
55
CANTOS study on targeting inflammation
56
Periodontal disease and atherosclerosis: Strengthening the oral-systemic link.
57
Mouth Bacteria Linked To Esophageal Cancer
58
Research May Explain Why Gum Disease Is Linked To Heart Disease
59